Istanbul – The appointment has come as coronation of an intensive research path conducted by Enzo Agostinelli at Sapienza University and in many foreign laboratories in the USA, Canada, Brazil, China, Japan, Taiwan, India, South Africa, Turkey, Russia and various European Union countries, as proven by numerous publications (over 130 contributions from articles and books published in prestigious international journals and more than 200 communications at national and international conferences) mainly dedicated to the identification of non-invasive cancer therapies based on the use of polyamines, aliphatic amines of low molecular weight, with an important role in the cell growth and differentiation. The international research group, coordinated by the biochemist of Sapienza, studying a new therapeutic application that uses the high polyamine content present in cancer cells, capable of becoming a source of cytotoxic metabolites as a result of interactions with specific metal enzymes belonging to the the amino oxidase group.
