(February 22, 2017) The International Foundation on Polyamines new president is Enzo Agostinelli, Professor of Biochemistry and Molecular Biology of Sapienza University, known for his research on non-invasive cancer therapy, opening new perspectives on the treatment of drug-resistant cancer. The international research group, coordinated by the biochemist of Sapienza, is studying a new therapeutic application that uses the high polyamine content present in cancer cells, capable of becoming a source of cytotoxic metabolites as a result of interactions with specific metal enzymes belonging to the amino oxidase group. “Our aim is to develop a therapy that prevents those, sometimes devastating, side effects that cancer patients are exposed to with current therapies,” explains Enzo Agostinelli, “and also to open new perspectives for those who suffer a halt in the treatment, due to the fact that cancer cells may develop over time a strong resistance to drugs “. (Red)
